The hair restoring effect of growth factor treatment with platelet rich plasma
The growth factors found in platelet rich plasma are exactly proportioned by Nature to regrow damaged tissues including hair follicles. They also include what is needed to bring a living but dormant follicle whose metabolism and normal behavior has been shut down under the influence of androgens specifically dihydrotestosterone (DHT).
The different growth factors play various roles like musicians in an orchestra. The combined effect of their effort is greater than the sum of the parts. In medicine this property is known as synergy and translates into 1 + 1 = 3. There is interplay between these ancient arbiters of renewal and regeneration that is emblematic of the beauty and mystery of Nature Herself.
The growth factors contained in platelet rich plasma are able to stimulate the stem cells that form the very stuff of each hair to be brought out of a prolonged hormone induced slumber. Like Rip Van Winkle they awake after a long sad sleep. Some have been dormant for years, a condition from which they had little hope of ever escaping.
The growth factors stimulate the newly awaked stem cells to multiply their numbers many times over. The newborn cells travel to the hair bulb where the magic happens and the hair forms. The result is a healthy new hair shaft that pushes its way up the center of the follicle seeking the sun.
The evolution of a dormant to an active hair follicle to normal
Androgens (DHT) forced the hair follicle to shrink in size and become dormant with its once lush blood supply drying up to a trickle. After being awaked by platelet rich plasma the stem cells begin giving birth to new generations of baby hair cells. This activity makes them hungry for food and energy. These resources depend on the follicle’s blood flow that was minimized during dormancy. Some of the infused growth factors and the drugs in Minca Scalp Spray stimulate the growth of small arteries and veins that feed the bulb of the hair follicle. After the blood flow is reestablished the follicle begins to enlarge normalizing its size, which also results in an increased diameter of the hair shaft. New normal sized hair shafts grow out of the recovered follicle.
Once all the players in the hair growth symphony gather together the music begins bringing us joy and happiness. The diameter of each hair increases, as do their numbers. This new growth covers the scalp giving your hair a healthy full feel and look.
What growth factors are found in platelet rich plasma?
Your blood is the source of the platelet rich plasma used to awaken your hair follicles. We use several tubes of blood drawn from you here in our office to prepare the platelet rich plasma in our laboratory.
The major growth factors found in platelet rich plasma include Platelet Derived Growth Factor (PDGF), Transforming Growth Factor beta (TGFβ), Vascular Endothelial Growth Factor (VEGF), basic Fibroblast Growth Factor (FGF), Epidermal Growth Factor (EGF) and Insulin-Like Growth Factor (IGF I).
These growth factors promote stem cell proliferation and development. This is one of the ways platelet rich plasma helps the dormant follicle to recover. A tremendous advantage of platelet rich plasma as the source for growth factors is its native source. Over the millennia through trial and error Nature selected and engineered the optimum recipe of growth factors and placed them in the platelet to promote human healing.